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What are my chances of developing post thrombotic syndrome ? Buffalo Vein Specialist
Friday, December 7, 2012

 

 

According to the latest medical research, there are some general statistics that can be applied to help you understand if you are at risk for developing PTS.

  • 60% of patients with DVT will NOT develop post thrombotic syndrome. This means you have a better than 50/50 chance of not developing the condition at all. However, some studies show that this percentage is closer to 50%, depending on other factors.

 

  • 30% of patients who suffer from DVT will have some symptoms of post thrombotic syndrome, though these symptoms can vary significantly from one patient to another. The severity of symptoms can also vary significantly.

 

  • 5% of patients who suffer from DVT will go on to develop severe post thrombotic syndrome that requires significant treatment to correct or mitigate. Severe symptoms can include leg ulcers, extreme pain and edema, “bursting” pain and limited mobility to name only a few.

 

  • If you have not suffered any symptoms of PTS in one and a half to two years after treatment for deep venous thrombosis, chances are that you will not develop post thrombotic syndrome at all. However, your doctor may recommend that you continue wearing compression stockings, though the compression strength may be adjusted.

 

  • Patients with ‘proximal’ DVT (upper calf) have a higher chance of developing post thrombotic syndrome (15% of patients). Thigh DVT or calf-to-thigh DVT seems to be the most common precursor to PTS.

 

  • There is no means to predict who will or will not develop post thrombotic syndrome with any degree of accuracy.

 

  • Interestingly, PTS is less common in patients with Factor V Leiden or the Prothrombin II gene mutation according to Khan and colleagues who have published an article called ‘Predictors of the PTS during long term treatment of proximal DVT’ (J Thrombosis and Haemostasis, volume 3, pages 718-723, 2005).

 

These are excerpts from Dr. Karamanoukian's book about the Post Thrombotic Syndrome (PTS) and Deep Vein Thrombosis:

 

Most cases of PTS present within six months of treatment for deep venous thrombosis, but some can take up to two years. In addition, each patient will have different symptoms and symptom combinations. The only true way to determine if you suffer from post thrombotic syndrome is to undergo an examination by a medical professional (preferably the doctor who treated your DVT).

 

The Villalta Scale was described in the 1990’s to diagnose and classify the severity of post thrombotic syndrome. Clinical studies done by Dr. Khan show that the Villalta scale is a “reliable, valid, acceptable and responsive measure of PTS in patients with previous, objectively confirmed DVT” and was published in the Journal of Thrombosis and Heamostasis (volume 7, pages 884-888, 2009).

 

Dr. hratch Karamanoukian is a member of the American College of Phlebology AND a Diplomate of the American Board of Phlebology. He can be contacted by calling 716-839-3638 or www.VeinsVeinsVeins.com 

 

 

Dr. Raffy Karamanoukian is a member of the American College of Phlebology AND a Diplomate of the American Board of Phlebology. He can be contacted by calling 310-998-5535 or www.SantaMonicaVeinCenter.com 

 

Drs. Raffy and Hratch Karamanoukian have authored 6 books about venous disease. The books are available on Amazon Kindle and Nook books for download.

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