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Vein Wall Changes and Vein Valve Disesae in Chronic Venous Disease
Friday, February 8, 2013



Chronic venous disease is associated with significant morbidity and reduction in quality of life (QOL) indicators. The two major mechanisms of venous disease in chronic venous disease is :


1) Hypoxia (low oxygen concentration) in the venous bloodstream and vein wall and


2) Alteration in the wall tension of the vein wall which results from venous hypertension and venous valvular insufficiency


Venous hypertension results in superficial venous reflux, deep venous reflux (insufficiency) or superficial and deep venous insufficiency.


Researchers have shown that venous hypertension due to venous insufficiency results in the symptoms constellation which is common - leg pain, heaviness, fatigue, cramping, throbbing, restless legs and leg swelling.


If you want to read about compression stockings in detail, read our book(s) - they are free on request by email - we will send them to you in pdf form. Dr. Raffy Karamanoukian and I have written 6 books about venous isnufficiency and varicose veins. - click to see our books


Comprehensive Information about the Venefit Procedure (VNUS Closure) at your fingertips by Buffalo Vein Expert Hratch Karamanoukian MD FACS, a Board Certified Phlebologist (Vein Specialist) - and


Information about EVLT Never Touch at your fingertips from Santa Monica Vein Expert Dr. Raffy Karamanoukian, a Board Certified Vein Expert - and


Dr. Hratch Karamanoukian is a member of the American College of Phlebology AND a Diplomate of the American Board of Phlebology. He can be contacted by calling 716-839-3638 



Dr. Raffy Karamanoukian is a member of the American College of Phlebology AND a Diplomate of the American Board of Phlebology. He can be contacted by calling 310-998-5535 


Drs. Raffy and Hratch Karamanoukian have authored 6 books about venous disease. The books are available on Amazon Kindle and Nook books for download.


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