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Validation of the Villalta Scoring System for Post Thrombotic Syndrome
Sunday, August 11, 2013



Post thrombotic syndrome (PTS) is a condition which results in leg pain, leg swelling, and in severe cases, lipodermatosclerosis and venous stasis ulcer formation.


To date, the Villalta score that is used to calculate the severity of post thrombotic syndrome has not been validated.


A recent study conducted by a group from the Epidemic Section of Vascular Surgery at the Imperial College School of Medicine, United Kingdom looked to validate the Villalta score. The study results were published in the Journal of Vascular Surgery, volume 57, pages 254 to 261.  The study was published in 2013 and looked at the scoring system used to diagnose and classify post thrombotic syndrome, which is a common chronic complication of deep vein thrombosis (DVT).


A systematic review of the literature pertaining to post thrombotic syndrome was done and the Prisma meta-analysis system and guidelines were used to analyze the data. The authors used the Villalta, Ginsberg, Widmer, CEAP, and venous clinical severity score system (VCSS) to assess the stated outcome measures. 


From their stated use in the literature, the authors concluded that the Villalta score was able to fulfill all the clinical criteria.  The authors also found that the main criticism of the Villalta score appears to be the use of subjective clinical measures.


The authors concluded from this study that the Villalta score combined with the venous disease specific quality of life questionnaire should be considered the “gold standard” for the diagnosis and classification of post thrombotic syndrome.


Dr. Hratch Karamanoukian has written a book about post thrombotic syndrome.  A free copy of this book can be obtained by contacting him via


For treatment of post thrombotic syndrome, contact Hratch Karamanoukian, MD FACS at the Vein Treatment Center or go to  or call 716-839-3638., are partners with



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