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K-T Syndrome - Klippel-Trenaunay Syndrome - Features - Vein Treatment Center Buffalo Niagara
Tuesday, August 13, 2013



Klippel-Trenaunay syndrome is a condition that affects the blood vessels, soft tissues and bony structures in the lower extremities.  This disorder has some characteristic features including port wine stains, overgrowth of soft tissue and bones, and venous malformations. 


Most people with the Klippel-Trenaunay syndrome are born with a port wine stain.  Klippel-Trenaunay syndrome is also associated with overgrowth of bone and soft tissues which begin during infancy. This abnormal growth is usually limited to one limb and most of the time, in the lower extremity.


The third major feature of the Klippel-Trenaunay syndrome is abnormalities of vascular structures including varicose veins which are engorged and occur near the surface of the skin (superficial veins).  Patients with Klippel-Trenaunay syndrome can also have abnormalities involving the deep vein structures of the limbs.  These malformations increase the risk of developing deep vein thrombosis and subsequent venous thromboembolism and pulmonary embolism.


The prevalence of Klippel-Trenaunay syndrome is one in one hundred thousand people and the inheritance pattern is sporadic and not inherited directly by genetic mutation that is passed down to the next generation.


Patients with venous abnormalities associated with the Klippel-Trenaunay syndrome can contact Hratch Karamanoukian, MD FACS at the Vein Treatment Center with offices in Williamsville, New York and Clarence, New York or contact him via or by calling 716-839-3638 to schedule a consultation. and are partners with



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