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Anticoagulation for DVT thrombophylaxis after hip surgery and knee surgery - Buffalo Niagara Vein Treatment Center and
Thursday, August 22, 2013



An article written by Dr. Kwong at the Department of Orthopedic Surgery at Harbor UCLA Medical Center in California reviewed the routine use of thrombophylaxis as a standard of care in the management of patients following total hip replacement and total knee replacement.  The article looks at agents such as enoxaparin which have been the standard for prophylaxis against deep vein thrombosis and thromboembolism.


The author states that the introduction of new pharmacologic agents have sought to address the issue of not only efficacy but also safety, ease of use of rivaroxaban and patient compliance.  The author states that oral agents such as rivaroxaban have demonstrated various degrees of efficacy over enoxaparin while preserving patient safety.


The author also shows that comparison of the relative efficacies of apixaban, dabigatran, and rivaroxaban (Xarelto) have shown rivaroxaban to be more efficacious than the other two in reducing symptomatic venous thromboembolism following total hip replacement and total knee replacement.


Dr. Kwong concluded that new oral antithrombotic agents have demonstrated efficacy in prophylaxis against venous thromboembolism following total hip or total knee replacement surgery while preserving safety – these agents increase the ease of administration of thrombophylaxis for both the patient and the physician.


This article was by Dr LM Kwong was published in Clnical Pharmacology 2013, volume 5, pages 143 - 148.


For the management and treatment of deep vein thrombosis and thromboembolism contact Hratch Karamanoukian, MD FACS at the Vein Treatment Center with offices in Williamsville, New York and Clarence, New York or contact him via or or call 716-839-3638.


Hratch Karamanoukian, MD FACS is board certified in surgery, thoracic surgery (cardiovascular surgery) and phlebology (diseases of the venous and lymphatic systems). or are partners with .







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