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Treatment of DVT and Venous Thromboembolism in Patients with Cancer - Buffalo Niagara Vein Treatment Center
Thursday, August 22, 2013



An article by Dr. Kleinjan and colleagues from the Department of Vascular Medicine, Academic Medical Center in Amsterdam, the Netherlands looked at the use of low molecular weight heparin (LMWH) as the preferred anticoagulant treatment over oral agents for venous thromboembolism in patients with cancer.


A worldwide survey was sent with 49 questions on different aspects of the treatment of patients with cancer and venous thromboembolism.  60% of the respondents completed the survey and the vast majority were from Europe (58%) followed by the United States (35%) and the remaining 7% from other countries.


Hematologists, oncologists, pulmonologists, and general internists responded to the questions.


Low molecular weight heparin (LMWH) was indicated as the first choice of treatment for the long term treatment of venous thromboembolism in patients with cancer by 82% of the respondents. 60% of the respondents used a full therapeutic dose of low molecular weight heparin and 40% chose a dose reduction. 


The authors concluded from the study that a relatively high observance rate of the guidelines with the use of low molecular weight heparin for long term treatment of venous thromboembolism in cancer was found.  It also found that the dose of low molecular weight heparin (full dose versus reduce dose) and the type of anticoagulant chosen after the initial 12 months of treatment varied substantially in different practices, namely choosing a vitamin K anticoagulant versus low molecular weight heparin.



For the management and treatment of deep vein thrombosis and thromboembolism contact Hratch Karamanoukian, MD FACS at the Vein Treatment Center with offices in Williamsville, New York and Clarence, New York or contact him via or or call 716-839-3638.


Hratch Karamanoukian, MD FACS is board certified in surgery, thoracic surgery (cardiovascular surgery) and phlebology (diseases of the venous and lymphatic systems). or are partners with




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